Suchen und Finden
Table of Contents
5
List of Contributors
12
Common Abbreviations
29
Biomarkers
31
The Diagnosis of Sepsis: The Present and The Future
32
Procalcitonin: Nice to Know, Need to know, or Needs Further Research?
39
Diagnostic and Prognostic Value of Hormokines as Biomarkers in Severe Infections
51
Novel Biomarkers and the Outcome from Critical Illness and Major Surgery
61
Molecular Approaches to Detection of Bacteria in Critical Care Patients
73
Sepsis and Infection: Management
82
Understanding and Optimizing Outcome in Neonates with Sepsis and Septic Shock
83
Effects of Vasoactive Agents on the Gastrointestinal Microcirculation in Septic Shock
97
Hemodynamic Effects of Activated Protein C in Septic Shock
103
Adrenomedullin in the Treatment of Cardiovascular Dysfunction and Sepsis
109
Antioxidants for the Treatment of Endothelial Dysfunction in Critical Illness
124
Plasma Cortisol: Time to Look Deeper?
134
Glucose Control and Monitoring in the ICU
141
Severe Lung Infections
158
Current Concepts of Severe Pneumococcal Community-acquired Pneumonia
159
Respiratory Syncytial Virus (RSV) in the Pediatric Intensive Care Unit
171
Pneumocystis Pneumonia in Non-AIDS Immunocompromised Patients
183
Mechanisms of Organ Dysfunction
197
The Role of Neutrophil-Derived Myeloperoxidase in Organ Dysfunction and Sepsis
198
Are Mitochondria Responsible for Improved Outcomes in Recent Studies?
213
The Impact of Chronic Disease on Response to Infection
222
Immunomodulatory Effects of General Anesthetics
233
Critical Illness Stress-induced Immune Suppression
242
Transcription Factors and Nuclear Cofactors in Muscle Wasting
254
Organ Dysfunction in the ICU: A Clinical Perspective
263
Lipids
271
Sphingolipid Metabolism in Systemic Inflammation
272
Statins in Sepsis and Acute Lung Injury
290
Potential Mechanisms by which Statins Modulate the Development of Acute Lung Injury
299
Acute Lung Injury
312
Matrix Metalloproteinases in Acute Lung Injury
313
The Role of Vascular Endothelial Growth Factor in Lung Injury and Repair
321
Cell Regeneration in Lung Injury
332
The Extracellular Matrix of the Lung: The Forgotten Friend!
342
Mechanical Ventilation
357
Advances in Translaryngeal Tube Technology
358
Is One Fixed Level of Assist Sufficient to Mechanically Ventilate Spontaneously Breathing Patients?
369
Patient-ventilator Interaction During Non-invasive Ventilation with the Helmet Interface
379
Protective Ventilation in Respiratory Failure
389
Dynamic Lung Imaging Techniques in Mechanically Ventilated Patients
390
Can We Protect the Lung from Acute Injury?
400
Rationale for High-Frequency Oscillation as a Primary Lung- Protective Mode in Patients with ALI/ ARDS
407
The Role of Protective Ventilation in Cardiac Surgery Patients
417
Alveolar Pressure/volume Curves Reflect Regional Lung Mechanics
426
Cardiovascular Topics
434
Cardiovascular Surgery in the Aging World
435
Intensive Care Unit Arrhythmias
449
Diastolic (Dys)Function in Sepsis
462
Autonomic Dysfunction: A Relevant Component in Multiple Organ Dysfunction Syndrome
473
Hemodynamic Monitoring
486
The Use of Hemodynamic Monitoring to Improve Patient Outcomes
487
Using Mathematical Models to Improve the Utility of Quantitative ICU Data
495
The Meaning of Hemodynamic Monitoring in Patients with Shock: Role of Echocardiography
509
Transpulmonary Thermodilution for Advanced Cardiorespiratory Monitoring
517
Using Heart-Lung Interactions for Functional Hemodynamic Monitoring: Important Factors beyond Preload
527
Diagnosis of Central Hypovolemia in a Spontaneously Breathing Patient
536
Assessment of Fluid Responsiveness in Spontaneously Breathing Patients
547
Passive Leg Raising
558
Extravascular Lung Water Measurement
565
Intravenous Fluid Therapy
576
Fluid Management in Sepsis: Colloids or Crystalloids?
577
Balanced Volume Replacement Strategy: Fact or Fiction?
588
Renal Failure
595
Cystatin C as a Marker of Renal Function in Critically Ill Patients at Risk for or with Acute Renal Failure
596
Adjustment of Antimicrobial Regimen in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy
605
Abdominal Pathologies
620
Abdominal Compartment Syndrome
621
Gut Absorption Capacity in the Critically Ill
639
The Liver
652
Critical Illness and the Hepatic Microcirculation: A Review
653
The Hepatic Response to Severe Injury
661
The Management of Liver Trauma
676
The Pathology and Management of Intracranial Hypertension in Acute Liver Failure
688
Neurological Issues
701
Continuous EEG Monitoring in the ICU
702
The Acute and Chronic Management of Large Cerebral Infarcts
714
Cooling Therapies after Neuronal Injury: Direct Brain Cooling and Systemic Hypothermia
724
Non-traumatic Subarachnoid Hemorrhage
730
Promising Concepts in Subarachnoid Hemorrhage
741
Nitric Oxide Metabolism after Traumatic Brain Injury
748
Modulation of Blood Pressure in Traumatic Brain Injury
757
The Delirious Patient in the ICU
766
Management of Burns
774
Emergency Room and Acute Care of the Critically Ill Burned Patient
775
Early Manipulation of Metabolic Changes due to Severe Burns in Children
786
Antithrombin in Burn Trauma
799
Hematological Alterations
805
The Critically Ill Red Blood Cell
806
Red Blood Cell Transfusion in the Pediatric ICU
820
Thrombocytopenia in Intensive Care Patients
830
Point-of-care Coagulation Monitoring: Current Status of Viscoelastic Techniques
841
Monitoring of Hemostasis in Emergency Medicine
854
Oral Anticoagulant Overdose and Bleeding Risk
868
Does Sex Make a Difference?
873
Insight into the Mechanism of Gender-specific Response to Trauma- hemorrhage
874
Sex-Related Differences in Response to Global Ischemic Insult and Treatment
885
Influence of Gender on Outcome of Severe Sepsis
894
Prognosis and Long- term Outcomes
902
The Changing Prognostic Determinants in the Critically Ill Patient
903
Chronic Critical Illness
912
To be or not to be ... Vegetative
922
Quality and Management
930
Intermediate Respiratory Care Units
931
The Impact of Noise in the Intensive Care Unit
944
Alarms: Transforming a Nuisance into a Reliable Tool
952
Ethical and Legal Dilemmas in Accessing Critical Care Services
960
Emergency Care for the VIP Patient
971
Brain Death: Compliance, Consequences and Care of the Adult Donor
978
Disasters
988
Update on Avian Influenza for Critical Care Physicians
989
Critical Care Pandemic Preparedness Primer
999
Pathobiology of Blast Injury
1011
Personal Reflections on Emergency Preparedness and the Response to A Major Natural Disaster: Hurricane Katrina
1023
Subject Index
1030
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