Handbook of Stress and the Brain Part 1 - The Neurobiology of Stress

Handbook of Stress and the Brain Part 1 - The Neurobiology of Stress

von: T. Steckler, N.H. Kalin, J.M.H.M. Reul

Elsevier Trade Monographs, 2005

ISBN: 9780080553245 , 856 Seiten

Format: PDF, OL

Kopierschutz: DRM

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Preis: 220,00 EUR

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Handbook of Stress and the Brain Part 1 - The Neurobiology of Stress


 

Front Cover

1

Handbook of Stress and the Brain: The Neurobiology of Stress

4

Copyright Page

5

Contents

16

List of Contributors

6

Preface

12

A Memorial for David de Wied (1925–2004)

14

Section 1: Concepts of Stress

20

Chapter 1.1. Stress: an historical perspective

22

Chapter 1.2. The neuropsychology of stress

44

Chapter 1.3. An introduction to the HPA axis

62

Chapter 1.4. Hormones of the pituitary

86

Chapter 1.5. Molecular biology of the HPA axis

98

Chapter 1.6. The hypothalamic–pituitary–adrenal axis as a dynamically organized system: lessons from exercising mice

114

Section 2: Hypothalamic Hormones Involved in Stress Responsivity

132

Chapter 2.1. Novel CRF family peptides and their receptors: an evolutionary analysis

134

Chapter 2.2. Molecular regulation of the CRF system

152

Chapter 2.3. Behavioral consequences of altered corticotropin-releasing factor activation in brain: a functionalist view of affective neuroscience

174

Chapter 2.4. The roles of urocortins 1, 2, and 3 in the brain

198

Chapter 2.5. Vasopressin and oxytocin

224

Chapter 2.6. The role of vasopressin in behaviors associated with aversive stimuli

250

Section 3: Stress and the HPA Axis

282

Chapter 3.1. Corticosteroid receptors and HPA-axis regulation

284

Chapter 3.2. Glucocorticoid effects on gene expression

314

Chapter 3.3. The role of 11ß-hydroxysteroid dehydrogenases in the regulation of corticosteroid activity in the brain

332

Chapter 3.4. Corticosteroids and the blood-brain barrier

348

Chapter 3.5. Glucocorticoids and motivated behaviour

360

Chapter 3.6. Effects of glucocorticoids on emotion and cognitive processes in animals

378

Chapter 3.7. Glucocorticoids: effects on human cognition

406

Section 4: Neurotransmitter Systems Involved in Stress Responsivity

422

Chapter 4.1. Neurocircuit regulation of the hypothalamo–pituitary–adrenocortical stress response – an overview

424

Chapter 4.2. Sympatho-adrenal activity and hypothalamic–pituitary–adrenal axis regulation

438

Chapter 4.3. The locus coeruleus–noradrenergic system and stress: modulation of arousal state and state-dependent behavioral processes

456

Chapter 4.4. Functional interactions between stress neuromediators and the locus coeruleus–norepinephrine system

484

Chapter 4.5. Regional specialisation in the central noradrenergic response to unconditioned and conditioned environmental stimuli

506

Chapter 4.6. Stress, corticotropin-releasing factor and serotonergic neurotransmission

522

Chapter 4.7. Modulation of glutamatergic and GABAergic neurotransmission by corticosteroid hormones and stress

544

Chapter 4.8. Neuroactive steroids

564

Chapter 4.9. Endogenous opioids, stress, and psychopathology

580

Chapter 4.10. Acetylcholinesterase as a window onto stress responses

604

Chapter 4.11. Pathways and transmitter interactions mediating an integrated stress response

628

Section 5: Neuroplasticity and Stress

660

Chapter 5.1. The intracellular signaling cascade and stress

662

Chapter 5.2. The role of neurotrophic factors in the stress response

684

Chapter 5.3. Transcription factors as modulators of stress responsivity

698

Chapter 5.4. Experience, structural plasticity and neurogenesis

718

Chapter 5.5. Adult neurogenesis in rodents and primates: functional implications

730

Chapter 5.6. Cellular and molecular analysis of stress-induced neurodegeneration – methodological considerations

748

Chapter 5.7. Enhancing resilience to stress: the role of signaling cascades

770

Section 6: The Stressed Brain

792

Chapter 6.1. Psychological and physiological stressors

794

Chapter 6.2. Involvement of the amygdala in the neuroendocrine and behavioral consequences of stress

812

Chapter 6.3. Role of prefrontal cortex in stress responsivity

826

Subject Index

838