Clinical Allergy - Diagnosis and Management

Clinical Allergy

Gerald W. Volcheck

Series Editor’s Introduction

Preface

Contents

Overview of the Human Immune Response

1.1 Introduction

1.2 Innate Immune System

1.3 Acquired Immune System

1.4 T- and B-Cells in the Acquired Immune Response

1.5 Lymphoid Tissues

1.6 Tolerance: Distinguishing Self from Nonself

1.7 Cytokines

1.8 Chemokines

1.9 Complement

1.10 Inflammatory Cells

1.11 Primary Mediators of Inflammation

1.12 Allergic Response to an Allergen: Summary

1.13 Immune-Modulating Medications in Allergic Disease

1.14 Summary

Suggested Reading

Environmental Allergens

2.1 Overview of Allergens

2.2 Pollens

2.3 Fungal Allergens

2.4 Indoor Allergens

2.5 Animal Allergens

2.6 Cockroach Allergen

2.7 Clinical Vignettes

Suggested Reading

Allergen Testing and Allergen Immunotherapy

3.1 Allergen Testing

3.2 Allergen Immunotherapy

3.3 Summary

3.4 Clinical Vignettes

Suggested Reading

Allergic Rhinitis and Rhinosinusitis

4.1 Overview

4.2 Nasal Anatomy and Function

4.3 Clinical Overview

4.4 Allergic Rhinitis

4.5 Nonallergic Rhinitis and Rhinosinusitis

4.6 Infectious-Acute Rhinosinusitis

4.7 Chronic Rhinosinusitis

4.8 Infectious Chronic Rhinosinusitis

4.9 Allergic Fungal Rhinosinusitis

4.10 Chronic Eosinophilic (Fungal or Hyperplastic) Rhinosinusitis

4.11 Systemic Disease

4.12 Noninfectious Structural Rhinosinusitis

4.13 Noninfectious Nonstructural Rhinitis and Rhinosinusitis

4.14 Clinical Vignettes

Suggested Reading

Allergic Eye Disease

5.1 Overview

5.2 Basic Eye Anatomy

5.3 Approach to the Patient

5.4 Allergic and Allergic-Like Eye Disease

5.5 Clinical Vignettes

Suggested Reading

Asthma

6.1 Overview

6.2 Epidemiology

6.3 Pathophysiology

6.4 Clinical Presentation and Differential Diagnosis

6.5 Classification of Asthma

6.6 Evaluation of Factors Contributing to Asthma Severity

6.7 Treatment

6.8 Clinical Vignettes

Suggested Reading

Urticaria and Angioedema

7.1 Description and Epidemiology

7.2 Pathophysiology

7.3 Acute Urticaria: Etiologies

7.4 Chronic Urticaria

7.5 Urticaria-Angioedema-Associated Disorders

7.6 Patient Evaluation

7.7 Medications Used in the Treatment of Acute and Chronic Urticaria

7.8 Therapy Recommendations

7.9 Clinical Vignettes

Suggested Reading

Atopic and Contact Dermatitis

8.1 Atopic Dermatitis

8.2 Contact Dermatitis

8.3 Clinical Vignettes

Suggested Reading

Drug Allergy

9.1 Epidemiology

9.2 Definitions

9.3 Pathophysiology and Clinical Manifestations

9.4 Clinical Evaluation of Suspected Drug Sensitivity

9.5 Therapy and Management

9.6 Special Medication Reactions

9.7 Clinical Vignettes

Suggested Reading

Food Allergy

10.1 Definitions

10.2 Epidemiology

10.3 Pathophysiology

10.4 Food Allergens

10.5 Approach to Patients

10.6 Clinical Disorders

10.7 Management

10.8 Food Additive Reactions

10.9 Summary

10.10 Clinical Vignettes

Suggested Reading

Anaphylaxis and Anaphylactoid Reactions

11.1 Definition and Epidemiology

11.2 Pathophysiology

11.3 History and Physical Examination

11.4 Risk Factors

11.5 Common Causes of Anaphylactic and Anaphylactoid Reactions

11.6 Idiopathic Anaphylaxis

11.7 Differential Diagnosis

11.8 Diagnosis and Diagnostic Testing

11.9 Management

11.10 Clinical Vignettes

Suggested Reading

Stinging Insect Allergy

12.1 Introduction

12.2 Identification of Stinging Insects

12.3 Reactions to Stinging Insects

12.4 Diagnostic Testing

12.5 Management

12.6 Conclusion

12.7 Clinical Vignettes

Suggested Reading

Index