Biochemistry of Atherosclerosis

This book covers many aspects of atherogenesis, with particular emphasis on lipid and lipoprotein metabolism. It includes all aspects of the regulation of cholesterol homeostasis and the importance of each pathway. Also explored are the roles of nuclear hormone receptors on lipid and lipoprotein metabolism and their complex roles in atherogenesis. The book further discusses how genetic studies can help understand the complexities that mediate these aspects of atherogenesis.


Dr. Sukhinder K. Cheema is Associate Professor of Biochemistry, Memorial University of Newfoundland, Canada. She has worked as a Research Scientist with the Nova-Husky Research Corporation in Alberta, Canada. She is currently researching the molecular mechanisms of cholesterol ester transfer protein regulation by dietary fats and hormones. She also researches the regulation of genes involved in cholesterol metabolism by hormone factors, the molecular basis of diabetes-accelerated atherosclerosis, and the mechanisms of lipid abnormalities caused by protease inhibitors.